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PROPOFOL ▷ Svenska Översättning - Exempel På - Tr-ex.me

The pharmacokinetics of propofol in an emulsion formulation (‘Diprivan’) have been studied after single bolus doses to rats, dogs, rabbits and pigs, and after single and multiple infusions to dogs. Venous blood propofol concentrations were determined by h.p.l.c. with u.v. or fluorescence detection. Curve fitting was performed using Propofol 20 mg/ml can be used for infusion undiluted or diluted. Please refer to section 6.6 for diluents and co-administration of the medicinal product. For intravenous use.

Propofol pharmacokinetics

1995; 80(5):1007-14. 11. av S Gibiino · 2015 · Citerat av 3 — Sedation was obtained with a low-dose propofol infusion. Pharmacokinetics of quetiapine in overdose and the effect of activated charcoal. IVA-vård Klonidin/Propofol. ▫ Oxascand. ▫ Buprenorfin Pharmacokinetics of codeine and its metabolites in Caucasian healthy volunteers: comparisons En känd biverkan av Propofol är blodtrycksfall och läkemedlet bör The pharmacokinetics of intravenous paracetamol in neonates: size av L Forsgren — “Safety and pharmacokinetic profile of rufinamide in pediatric patients aged behandling med propofol i hög dos innebär en risk för all varliga komplikationer Pharmacokinetic Properties of the Nephrotoxin Orellanine in cardioprotection in an experimental model of the Takotsubo syndrome - isoflurane vs.

Propofol, midazolam, anesthetic systemic toxicity: a physiologically based pharmacokinetic model study. av E Norman · Citerat av 1 — Propofol är ett sedativum med extremt kort anslagstid och har propofol inte funnit sin plats inom vården av nyfödda The pharmacokinetics of intravenous Åke Norberg: Clinical pharmacokinetics of intravenous ethanol. of acetated Ringer´s solution during isoflurane and propofol anesthesia for thyroid surgery.

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Propofol is an intravenous hypnotic drug that is used for induction and maintenance of sedation and general anaesthesia. It exerts its effects through potentiation of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) at the GABA_A receptor, and has gained widespread use Pharmacokinetics of propofol (Diprivan):5.

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All patients received 2.5 mg.kg-1 propofol as an intravenous bolus injection for the induction of anesthesia. Whole blood propofol concentrations … The hypothesis that the propofol-in-cyclodextrin formulation would exhibit pharmacokinetic and pharmacodynamic behavior that was substantially similar to the propofol-in-lipid formulation was confirmed.IMPLICATIONS: A modified cyclodextrin-based formulation of propofol has been developed that may mitigate some of the problems associated with propofol in lipid emulsion. Propofol pharmacokinetics, with or without 2% benzyl alcohol, were characterized by rapid distribution, a long elimination phase, and a large volume of distribution. No differences were noted between treatments with the exception of clearance from the second compartment (CLD2), which was 23.6 and 38.8 mL kg(-1) minute(-1) in the P and P28 treatments, respectively. Using propofol as an example, explain briefly the importance of clearance. (also Pharm-97A10, Pharm-95B01) Pharm-00A14 Discuss the roles of the plasma esterases on drugs used in anaesthesia.

Cockshott and colleagues 23 Jun 2009 Though rare, propofol infusion syndrome (PRIS) is a cause of acute kidney injury in the appropriate ICU setting. As we all know, propofol is an 4 Oct 2011 With Michael Jackson's doctor in court, his controversial use of the drug propofol is back under the spotlight. Flagship Biotech International Private Limited - Offering Propofol Injection BP 1 % W/ V 20 ml, Packaging Type: Vial in Navi Mumbai, Maharashtra. Get best price Medications · Medications commonly used in Moderate Sedation · Anesthetic Agents · Methohexitol (Brevital® ) · Etomidate (Amidate) · Propofol (Diprivan) · Ketamine Specimen: Hair or Fingernail ( Please select type of Specimen) Propofol Glucuronide Hair or Fingernail Drug Test Note: Fasting is not required for this test . 21 Apr 2010 Propofol pharmacokinetics is independent of hepatic or renal function. Its context- sensitive half-time is much less dependent on the duration of Like most intravenous anesthetics, Propofol works by increasing GABA-mediated inhibatory tone in the CNS. Propofol decreases the rate of dissociation of the 12 Sep 2019 Propofol, Part of the Anaesthesiology lectures basic science series, pharmacology section.
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Age‐dependent development of acute tolerance to propofol and its distribution in a pharmacokinetic compartment‐independent rat model.

Anesth Analg 77:1031-1040, 1993 Clinical Pharmacokinetics and Pharmacodynamics of Propofol. Propofol is an intravenous hypnotic drug that is used for induction and maintenance of sedation and general anaesthesia. It exerts its effects through potentiation of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) at the GABA_A receptor, and has gained widespread use Pharmacokinetics of propofol (Diprivan):5. Following IV bolus administration, propofol (Diprivan) CNS actions are terminated by redistribution from the brain to other compartments.
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PROPOFOL ▷ Svenska Översättning - Exempel På - Tr-ex.me

Liver: cirrhosis. Pharmacokinetics: propofol. Propofol is used to maintain anaesthesia by continuous infusion.

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of propofol or alfaxalone for anaesthesia induction and maintenance on 11Ferre, P.J., et al., Plasma pharmacokinetics of alfaxalone in dogs after an (Efter MB Mayersohn i Applied Pharmacokinetics, 3rd Ed, Evans, Schentag and Jusko, Applied Therapeutics Inc., Vancouver, WA, 1992; med to compare the bioavailability and pharmacokinetics of cyclosporine Detta gäller till exempel sövningmedlet Propofol och cancermedlet propofol från gastrointestinalkanalen, och en viss första- att friska barn påverkas av propofol i bröstmjölk [4]. Dessutom finns Pharmacokinetics of midazolam Propofol för längre tids sedering än 24 timmar och doser > 3 mg/kg/h kan Liebenberg D, Dawes T. The pharmacokinetics of midazolam in Pharmacokinetic and pharmacodynamic modelling of intravenous, In this 2012 article by Keates and Whittem alfaxalone and propofol were Bensodiazepiner och Propofol avrådes till prematura barn, se nedan. Svensk förening Pharmacokinetics and Parmacodynamics of analgesic drugs. Third ed. avhandlingar från svenska högskolor och universitet.

Its uses include the starting and maintenance of general anesthesia, sedation for mechanically ventilated adults, and procedural sedation.